A list item in an F2 Lookup can be setup to retrieve information from your contact manager. For salesforce.com you can retrieve company or contact information. For a list of fields that you can use, go into the DataLink setup where you add a new field mapping and in the Contact Manager Field drop down you will see a list of all the available fields that can be used.
Example:
~Salesforce_Macro (contact->phone_home)
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